口服A酸治療痘痘也可能有背痛與關節發炎的副作用

2/24/2020 0 評論

口服A酸治療痘痘也可能有背痛與關節發炎的副作用

口服A酸能減少高達9成的皮脂腺分泌量、抑制發炎反應，治療痘痘效果卓越。但您知道它可能引起背痛與關節發炎嗎？

除了(1) 皮膚與口鼻黏膜乾燥、(2) 肝指數、血脂肪、膽固醇上升、(3) 憂鬱症、(4) 致畸胎等常聽到的風險要小心，近年來醫學界注意到口服A酸可能導致關節疼痛的問題。

研究發現，在使用口服A酸治療青春痘的人當中，有23.98%的人出現背痛症狀，這當中有42.3%的人(也就是10%使用口服A酸的人) 經電腦斷層掃描檢查後，證實有薦腸骨關節炎。該研究口服A酸的每日劑量為每公斤0.5~1 mg。

背痛症狀是在用藥大約3.4個月後開始出現，但是能在停藥約6.27個月後完全緩解。

提醒大家 :

口服A酸為痘痘治療的二線用藥，請先針對使用劑量與安全監測，擬定治療計畫。

多數皮膚科醫師不在一開始都開立口服A酸治療發炎性的青春痘，主要是考慮其副作用。

參考資料：

Clin Rheumatol (2020) 39:1829–1838

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醫師小叮嚀

青春痘是橫跨10~50歲的皮膚問題。不僅是影響美觀，還可能造成發炎感染與永久疤痕。皮膚科張宜菁醫師、北醫美容醫學中心主任，教您如何對抗痘痘與告別痘疤。對付痘痘最好的方法，是借助專業醫學，搭配生活保養。請避免輕信傳言！

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醫美如何美感自然又安全，皮膚問題怎麼照顧，讓留學美國哈佛皮膚科的張宜菁醫師，提供正確醫療新知

預約張宜菁主任美容醫學諮詢與治療，請來電北醫附設醫院皮膚科(02)66367135, CHANGSKINLASER@GMAIL.COM

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美容醫學療程效果因人而異，術後可能有風險與副作用。術前請諮詢專業醫師，並注重術後照護。

雷射等美容醫學光電療程術後可能有皮膚紅腫、黑色素沉澱、單純皰疹復發、灼傷等副作用

電波療程術後可能有泛紅、水腫、緊繃感。少數情況有水泡、燙傷、疤痕、單純泡疹復發等副作用。

音波療程術後可能有泛紅、水腫、緊繃感。少數情況有水泡、神經麻痺、燙傷、疤痕、單純泡疹復發等副作用。

玻尿酸填充劑注射術後可能有瘀青、紅腫、局部腫塊、單純泡疹復發、皮膚壞死、感染等副作用。

肉毒桿菌素注射術後可能有表情不自然、頭痛、眉形改變、眼皮下垂等副作用

倍克脂注射術後可能有瘀青、腫脹、疼痛、毛髮脫落、吞嚥困難、皮膚局部壞死、感染、神經受傷等副作用。

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